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CAS Number: 1007207-67-1
with an IC₅₀ in the nanomolar range
690206-97-4
InChi: InChI=1S/C82H103ClN18O16
CAS Number: 1225278-16-9
Dolutegravir - CAS# 1051375-16-6 Catalog No.:M11383-2 CAS Number: 1007207-67-1Dolutegravir, also known as GSK1349572, is a potent inhibitor of HIV integrase with an IC50 value of 2. 7 nM for HIV 1 integrase catalyzed strand transfer in vitro. 1 It inhibits HIV 1 viral replication (EC50 = 0. 51 nM) in peripheral blood mononuclear cells (PBMCs). Dolutegravir (DTG) is an antiretroviral medication used, together with other medication, to treat HIV AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV
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